NYU Abu Dhabi Researchers Create Rapid Paper-Based Diagnostic Tool For Infectious Disease Detection

A team of researchers at NYU Abu Dhabi has created a paper-based diagnostic tool that can identify COVID-19 and other infectious diseases in less than 10 minutes. This device, known as the Radially Compartmentalized Paper Chip (RCP-Chip), does not require advanced laboratory equipment or trained personnel, offering a quick and cost-effective solution for on-site disease screening.

The RCP-Chip is designed to detect even small amounts of viral genetic material using just a droplet of fluid, resulting in a visible colour change. It functions without electricity or specialised equipment, needing only mild heat around 65°C, akin to warm water temperature. This makes it ideal for use in low-resource settings.

Researchers from the Advanced Microfluidics and Microdevices Laboratory (AMMLab) engineered this innovative chip. The study detailing its development is published in the journal Advanced Sensor Research under the title "Single-Layer Radially Compartmentalized Paper Chip (RCP-Chip) for Rapid Isothermal Multiplex Detection of SARS-CoV-2 Gene Targets." This research highlights the RCP-Chip's potential as a rapid diagnostic platform.

Mohammad A. Qasaimeh, an Associate Professor at NYUAD, emphasised the chip's real-world applications. He stated, "The RCP-Chip is designed for real-world impact. It can be reconfigured to detect other infectious diseases, making it a powerful tool for global health." This adaptability makes it valuable for addressing various health challenges globally.

Pavithra Sukumar, a Research Assistant at NYUAD and co-first author of the study, highlighted the test's practicality: "This is a fast, affordable, lab-free test that detects multiple gene targets in under 10 minutes." She noted its potential to enhance outbreak responses by enabling quicker isolation and treatment measures.

The RCP-Chip represents a significant advancement in diagnostic technology by providing an accessible and efficient method for detecting infectious diseases. Its ability to function without complex infrastructure makes it particularly beneficial for regions with limited resources.

This development could transform how outbreaks are managed by allowing rapid testing and response. By facilitating faster isolation and treatment processes, it holds promise for improving public health outcomes worldwide.

With inputs from WAM